Year  2020

Stage I. Synthesis and characterization of the precursors

Year 2021

Stage II. Design, synthesis and characterization of peptide-functionalized magnetic nanocarriers loaded with dexamethasone

Preparation of peptide-functionalized magnetic nanocapsules loaded with dexamethasone

Preparation of peptide-functionalized magnetic liposomes loaded with dexamethasone

Year 2022

Stage III. In vitro behaviour of peptide-functionalized magnetic nanocarriers loaded with dexamethasone

 

Fluorescent peptides-functionalized magnetic nanocarriers

 

In vitro drug release studies

 

 

Evaluation of the in vitro drug delivery to the inner ear using an artificial mucosa model

 

 

Biodegradability studies of oligochitosan-based nanocarriers

 

Assessment of the in vitro cytotoxicity

 

 

 

Year 2023

Stage 4 – In vitro investigation of protein adsorption, hemolysis and behaviour of the peptide-functionalized magnetic nanocarriers at the cellular level

 

In vitro assessment of the interaction of peptide-functionalized magnetic nanocarriers with the blood components

 

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